DraStic DS Emulator: Pokemon Black and White 2 - Gender Modifier?

I'm not really sure if this is the right thread so please correct me if I'm wrong.

I've a series of questions here:

":Gender Modifier
:::Save game and reset. Permanent effect. 2221E3A5

::Boy
62000024 00000000
B2000024 00000000
20019D41 00000000
D2000000 00000000

::Girl
62000024 00000000
B2000024 00000000
20019D41 00000001
D2000000 00000000"

I know this code works, but I'm just starting to play the game and I'm kind of new to the emulator as well, but does this code work for everything in-game?

I mean, if you start off as a girl, the game will treat you as a girl the whole time; and if I understood right, some characters (Curtis and Yancy, I believe.) also change depending on your initial gender.

But if you use this cheat and change to a boy, will the game permanently treat you as a boy and change everything that goes along with it? Or will it still treat you as a girl with Curtis despite having a male sprite? Oh, also...can you simultaneously change from one gender to the other and change the other characters as well?

And what about the PokeStudios? Will they be affected too?

I'm just really curious. I don't really want to be paired with Curtis despite being a male or vice versa with Yancy or crash the game altogether. Help?