I'll have to say frieza saga just because that's the one that i watched the most and i like frieza as well.
I have to agree, the Frieza saga was the sh*t. The Goku vs. Frieza battle was epic. I love the way Frieza crushed Krillin. Then Goku for the first time turned into Super Saiyan 2. Good times. H.
The entirety of the Android Saga (i.e. Trunks, Androids, Imperfect, Perfect, Cell Games.) It was a refreshing idea on the series, and actually gave some of the "B Squad" members some action moments (i.e. Tien's Kikoho vs. #17 absored Cell.) The ending was perfect. WE got to see Piccolo, Krillin, Yamcha, Tien, and Vegeta collective aid Gohan in the final beam struggle against Cell. After it was over, Goku passed the torch to his son and entrusted the safety of Earth to his friends.